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Low Dose Naltrexone

An alternative treatment for Autoimmune Diseases

Low Dose Naltrexone is widely prescribed in the UK as an off-label (unlicensed) treatment for Autoimmune diseases.

It was originally developed as Naltrexone Tablets, used in Opiate addiction - in doses of 50-200mg daily.

In the 1980s, Dr Bernard Bhairi discovered that Naltrexone, when given in smaller amounts, had beneficial effects on the immune system.

Since the 1980s, LDN has been used for the treatment of HIV, Cancer and various immune disorders - with varying levels of success.

Since then, Doctors have conducted many mini-studies on patients with untreatable Autoimmune diseases - who have not responded to conventional treatment.

Most commonly:

  • Multiple Sclerosis
  • Crohns Disease
  • Lupus
  • Arthritis

and it is becoming very popular as an alternative treatment to commonly used immunosuppressants, due to the few side effects and great improvements some patients have anecdotally made.

There are several websites helping to raise awareness of this treatment and try to get it to be commonly prescribed on the NHS.

LDNNow - Dr Chris Steele MBE talks about Low Dose Naltrexone (LDN)

Why can I not get it from my normal GP?

LDN is an unlicensed treatment. This means that it has not undergone large scale clinical trials - most of the evidence for its use come from anecdotal examples of improvement, or small scale clinical studies.

A number of studies have been conducted into using it in Crohns disease - with excellent results - but no large scale studies into Autoimmune disease have been completed.

As there have been no large scale trials, your normal GP - who is not a specialist in treatment with LDN - will be very wary of prescribing it, as it does not have the clinical trial data to backup its use.

The doctors at Prescribe4me have been trained by the current specialists in LDN prescribing, and are comfortable to competent to prescribe it safely "off-label" or in an unlicensed form - without having a clinical trial to back it up.

Why have there not been any clinical trials?

Clinical trials cost money - Naltrexone has been a "Generic" drug for many years.

This means that no drug company can patent the drug for use in Autoimmune disease - thereby meaning they could not recoup the cost of a clinical trial by selling the drug.

Some online stories regarding LDN

How do I get a prescription for LDN?

Click on the button.

Because LDN is an unlicensed drug and is not generally available in the community, an online-only consultation is not enough.

Once you click on the START consultation, there is a brief questionnaire to be filled in, and then one of our doctors specifically trained in LDN use will call you back.

This telephone consultation service costs £30 and includes the first 28 days prescription for LDN. You will only be charged if the doctor decides that you are suitable for LDN treatment. Repeat prescriptions are then issued every 3 months, at a cost of £14.50. LDN can take up to 6 months at maximum dose to reach full benefit.

Please note, we may request other information from you - such as a confirmation of diagnosis from your GP, or a letter of comfort from your own GP - allowing us to prescribe this medication for you. You will not be charged if we decide we cannot prescribe LDN for you in your circumstances.

When will we generally prescribe LDN?

If you have a formal diagnosis of:

  • Multiple Sclerosis
  • Fibromyalgia
  • Psoriasis
  • Crohns disease
  • Lupus
  • Ankylosing Spondilitis

or a diagnosis of an autoimmune disease in the list available at this link AUTOIMMUNE DISEASE LINK - then we will definitely consider you for LDN treatment.

If you have a formal diagnosis of:

  • A certain type of female infertility - and your fertility doctor has recommended that you try LDN.
  • HIV, and are currently not taking anti-retrovirals because your cell count is still quite high.
  • Certain cancers, where historically immunotherapy has shown a benefit - and you have not refused conventional treatment. (We can also provide the Berkson Protocol)

(Berkson Link):

If you have HIV/AIDS, we will happily have a consultation with you - but the process may not be so simple, we may refer you to a local specialist.

We will pass the prescription directly onto HomeDeliveryPharmacy / Dickson Chemist in Glasgow - as they are the most experienced supplier of LDN in the UK.

One month of LDN Liquid costs £17.50. They are happy to ship LDN to any European country - and elsewhere by arrangement. Please contact them directly on 0141 647 8032 for more information.

Dr Tom Gilhooly on LDN

Read some of the latest scholarly articles on LDN here: www.ldnaware.org